![]() ![]() Highly porous CGN single 3D-scaffolds have been used to support in vitro growth of many types of tissues. On the other hand, collagen (CGN) is one of the most widely used matrix biomaterial in tissue engineering. Title: Collagen/chitosan hybrid 3D-scaffolds as potential biomaterials for tissue engineeringĪuthors: Hilary Ureña-Saborio Emilia Alfaro-Viquez Daniel Esquivel-Alvarado Marianelly Esquivel Sergio Madrigal-CarballoĪddresses: National Center for Biotechnological Innovations (CENIBiot), CeNAT-CONARE, 1174-1200 San Jose, Costa Rica ' National Center for Biotechnological Innovations (CENIBiot), CeNAT-CONARE, 1174-1200 San Jose, Costa Rica ' National Center for Biotechnological Innovations (CENIBiot), CeNAT-CONARE, 1174-1200 San Jose, Costa Rica ' Polymers Research Laboratory (POLIUNA), School of Chemistry, National University, 86-3000 Heredia, Costa Rica ' National Center for Biotechnological Innovations (CENIBiot), CeNAT-CONARE, 1174-1200 San Jose, Costa Rica Polymers Research Laboratory (POLIUNA), School of Chemistry, National University, 86-3000 Heredia, Costa RicaĪbstract: Chitosan (CHT) has been reported to be biocompatible, bio-absorbable and particularly, is considered a good wound-healing accelerator. International Journal of Nano and Biomaterials.Inderscience Publishers - linking academia, business and industry through research Cell culture incubation with adipose tissue-derived stem cell (ADSC) and SEM imaging showed that CGN/CHT hybrid 3D-scaffolds allowed ADSC adhering, spreading, and growing in vitro. Hybrid 3D-scaffolds showed improved stability, greater porosity, increased thermal stability and mechanical properties, as well higher biodegradation as compared to single 3D-scaffolds. CGN/CHT hybrid 3D-scaffolds were characterised according to its water uptake capacity, mechanical properties, thermal behaviour (TGA), and morphology (SEM). ![]() We fabricated hybrid 3D-scaffold biomaterials by mixing CHT from native shrimp waste streams and CGN from tilapia aquaculture waste by-products, applying previously developed methodologies involving solvent casting and freeze-drying. Article: Collagen/chitosan hybrid 3D-scaffolds as potential biomaterials for tissue engineering Journal: International Journal of Nano and Biomaterials (IJNBM) 2018 Vol.7 No.3 pp.163 - 175 Abstract: Chitosan (CHT) has been reported to be biocompatible, bio-absorbable and particularly, is considered a good wound-healing accelerator. ![]()
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